Want to know more about Alzheimer's disease and genetic testing? Dive into our tools, resources, and news updates to help expand your understanding.

What is the genoSCORE-ACT Alzheimer's risk test?

Do you wonder how the genoSCORE-ACT Alzheimer's risk test works? In this video we walk you through the process from order to receiving your results.

Why I've decided to get a test

Rants and Big Pants as she is known on Instagram and Facebook shares why she has decided to take the test to find out her genetic risk.

Alzheimer's Society's checklist for possible symptoms

The Alzheimer's Society has created a helpful checklist for possible dementia symptoms. If you're worried about signs of dementia, use this checklist to describe your symptoms to a healthcare professional.

Alzheimer's Society's guide to caring for a person with dementia

Caring for a spouse, parent, or loved one with Alzheimer's can be difficult. This guide from the Alzheimer's Society gives you fantastic tools to help care for those with the disease.

Alzheimer's Society's Memory Handbook

Memory loss can be frustrating for both those with Alzheimer's and the people close to them. This handbook from the Alzheimer's Society provides ideas and practical strategies to help with living well.

Alzheimer's Society's guide to reducing your risk

Once you've found out your personal risk score for Alzheimer's disease, use this guide from the Alzheimer's Scoeity to create a brain health plan.

Lilly's Alzheimer's drug succeeds in phase III trial

The pharmaceutical company Eli Lilly announced successful Phase III clinical trial results for its Alzheimer's drug donanemab. The study showed that individuals taking the drug had a slower rate of decline in memory and thinking skills. Similar, positive results were shown by another drug, lecanemab (Biogen/Eisai), in January 2023.

BBC: Can slow breathing guard against Alzheimer's?

Researchers may have found another benefit of slow, controlled breathing - surprisingly it might help protect against Alzheimer's disease. In this study, researchers measured biomarkers in blood plasma that are associated with a higher risk of developing Alzheimer's and found that deep breathing helped reduce proteins in the blood related to the disease.

New report calls for manifesto pledges to tackle completely unacceptable diagnosis rates

One in three people living with dementia in the UK never received a formal diagnosis, a new report from Alzheimer's Research UK shows. They are encouraging leaders of political parties to put more focus on tackling the increasing pressure that dementia places on society, the NHS, and the economy.

The Mirror: New dementia treatment hope for Alzheimer's disease stemming from regular exercise

A new study shows that the hormone released while people exercise has been found to reduce sticky amyloid plaques that stop brain cells from communicating in Alzheimer's disease. It may be possible to literally run off the threat of Alzheimer’s disease

Alzheimer's Research UK: Brain Health Check-In tool

Did you know that just as we can look after other parts of our physical health, we can take steps to keep our brains healthy and help reduce the risk of dementia later in life? This Check-In from Alzheimer's Research UK will help you explore brain healthy behaviours and give you simple tips on how to give your brain some love.

NHS: 8 tips for healthy eating

Knowing your genetic risk for Alzheimer's can give you reassurance, or help you prepare for the future. It also encourages you to make changes, such as reducing your weight and eating healthy foods, to slow the onset of the disease. In this guide from the NHS you can find tips for healthy eating.

NHS: Physical activity guidelines for adults aged 19-64

Staying fit and healthy has been found to reduce the risk of Alzheimer's disease, or slow the onset. But how much physical activity should you be doing? This page from the NHS website offers guidance on daily activities that can keep the heart rate up.

Dr Jeff Gelblum talks about the benefits of knowing your risk

American Dr Jeff Gelbum offers a genoSCORE risk test in the US. He recently appeared on a podcast discussing why it is important to understand yur genetic risk and why APOE doesn't tell the full story.

Dr Richard answers your questions about genoSCORE-ACT

Dr Richard Pither has answered your questions about genoSCORE-ACT, from why you should get tested to how the test actually works.

Paul’s mother was diagnosed with Alzheimer’s and when he began to experience some memory issues and considering his previous history of depression, he took  the genoSCORE-ACT test to understand his genetic risk. 
The result showed his APOE genotype as E3/E3 and his personal risk score as 0.2*. This indicated that Paul was at a lower genetic risk of developing the disease. 
The test helped reassure Paul that his symptoms were unlikely to be related to Alzheimer’s. After the test, he received follow-up procedures from medical professionals to identify the reason for his memory issues. 

Paul’s Story

Susan, 55, had a family history of Alzheimer’s disease, with both her mother and grandparents having been diagnosed with the disease. She used genoSCORE-ACT to understand her genetic risk. When she took the test she was not experiencing any signs or symptoms of the disease.
The test showed her personal risk score to be 0.8* and her APOE genotype to be E4/E4. She was therefore identified at higher risk of developing Alzheimer’s disease.
Being aware of her personal genetic risk for the disease will help her act on any cognitive change she might experience in the future. After she found out her risk score, she received counselling on lifestyle changes she could consider to help prevent or delay the onset of the disease. 

Susan's Story

George’s mother suffered from Alzheimer’s disease, and so, aged 50, he decided to use the test to find out about his own risk. 
His test showed his personal risk score to be 0.6* and his APOE genotype to be E3/E4. This result identified George at average risk of developing Alzheimer’s.  
Armed with this result, George could consider the steps he could take to reduce his overall risk further. He took immediate action to reduce his weight and get better control of his high blood pressure with the help of his doctor. He also got support to begin  the Mediterranean diet, which focuses on plant-based foods and lean protein, and he began a daily exercise programme.

George’s Story 

*The genoSCORE-ACT personal risk score ranges from 0 to 1 and is therefore easy to understand. Risk scores are also categorised as LOWER, AVERAGE AND HIGHER. This denotes results that are lower, about the same or higher than that of the population as a whole. In addition, each personal risk report includes details of the individual’s APOE genotype.